Give your body a fighting chance to treat your fever, muscle aches, blisters, and other symptoms caused by the herpes simplex virus. Acyclovir is the first antiviral drug developed to relieve pain and discomfort caused by the herpes simplex virus 1 and 2. By slowing the growth and spread of the herpes virus, Acyclovir lessens the symptoms and shortens the length of time you are sick.

Side effects: Nausea, vomiting, diarrhea, decreased appetite, abdominal pain, headache, lightheadedness, or joint pain.
продолжить »

Improper nutritional constituents and abnormal consumption of fat rich edibles leads to raised blood pressure. Emotional stress and anxiety are some other causes of hypertension. Norvasc of Pfizer Pharmaceuticals is one potent remedy of the many available in the market. Chemically composed of Amlodipine, the drug treats angina pectoris and coronary diseases effectively.

As a potent calcium channel blocker, Norvasc reduced the contraction of the smooth muscles of the systemic blood vessels and reduces the vasoconstriction of the blood vessels as occurring in hypertension. Blood flow is retained to smooth levels and cholesterol deposition in the vascular lumen wall is compensated.
продолжить »

Cimetidine can increase the hypoglycaemic effects of gltptzide, gliclazide and possibly ghbenclamide in diabetics and there is the risk of excessive hypoglycaemta Ranitidine appears to behave similarly. The clinical relevance of other studies in normal subjects is uncertain some report that no significant interactions occur in normal subjects with tolbutamide, ghbenclamide, chlorpropamide or ghpizide and cimetidine, whereas one says that the effects of ghbenclamide are reduced by cimetidine and ranitidine. Cimehdine increases the serum levels of Glucophage.

Clinical evidence
Studies in diabetic patients given sulphonylureas
Six diabetics were given 400 mg cimetidine 1 h before taking a dose of ghpizide (average 5 7 mg dose) and then 3 h later they were given a standard meal with 200 mg of cimetidine. The expected rise in blood sugar levels after the meal was reduced by 40% and m three of the patients it fell to less than 3 mmol/1. In another report an elderly diabetic taking 160 mg ghpizide daily developed very low blood sugar levels (1 mmol/1) after starting treatment with 800 mg cimetidine daily. A study in diabetics mdicated that ranitidine can also increase the effects of ghpizide. Marked hypoglycaemia was seen in a patient on ghbenclamide when treated with ranitidine.

Studies in normal subjects given sulphonylureas
A study in seven subjects, given 250 mg tolbutamide daily for four days, showed that when additionally given 800 mg cimetidine daily for a further four days the pharmacokinetics of the tolbutamide were not significantly changed. Another study found no interaction between tolbutamide and cimetidine. Other studies in normal subjects showed that 800 mg cimetidine daily for seven days had no significant effect on the serum levels or the pharmacokinetics of tolbutamide or chlorpropamide. The hypoglycaemic activities of tolbutamide, chlorpropamide, glibendamide and ghpizide remained unaltered. In contrast in another study the AUC of tolbutamide was found to be increased by 20% and the elimination half life decreased by 17% by 1200 mg cimehdme, but plasma glucose levels were not significantly changed Ranitidine had no effect. Yet another study reported that the hypoglycaemic effects of ghbenclamide were reduced by cimetidine and ranitidine
продолжить »